Specifically PNPLA3-Mediated Accumulation of Liver Fat in Obese Patients with Type 2 Diabetes

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Association of PNPLA3 SNP rs738409 with liver density in African Americans with type 2 diabetes mellitus.

AIM Non-alcoholic fatty liver disease (NAFLD) is commonly diagnosed in patients with obesity and type 2 diabetes mellitus (T2DM), and has been associated with the single nucleotide polymorphism (SNP) rs738409 in the PNPLA3 gene. This association remains to be investigated in African Americans with T2DM, a group at lower risk for hepatic steatosis relative to European Americans with T2DM. METH...

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ژورنال

عنوان ژورنال: Endocrinology

سال: 2010

ISSN: 0013-7227,1945-7170

DOI: 10.1210/endo.151.10.9996